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Although most attenuated vaccines are viral, some are bacterial in nature.Examples include the viral diseases yellow fever, measles, mumps, and rubella, and the bacterial disease typhoid.A monovalent vaccine is designed to immunize against a single antigen or single microorganism.The valency of a multivalent vaccine may be denoted with a Greek or Latin prefix (e.g., tetravalent or quadrivalent).

Vaccines also help prevent the development of antibiotic resistance.widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the restriction of diseases such as polio, measles, and tetanus from much of the world.The effectiveness of vaccination has been widely studied and verified; for example, the influenza vaccine, The terms vaccine and vaccination are derived from Variolae vaccinae (smallpox of the cow), the term devised by Edward Jenner to denote cowpox.Fifty-four of those infections were associated with importation from another country, although only 13% were actually acquired outside the United States; 63 of the 64 individuals either had never been vaccinated against measles or were uncertain whether they had been vaccinated.Vaccines have contributed to the eradication of smallpox, one of the most contagious and deadly diseases in humans.

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